The portfolio of CD (chemically defined) CHO cell culture media developed for commercial CHO cell lines, including a variety of basal media, feed media, and perfusion media, which can support the expansion and protein expression of different CHO cell lines (CHO-K1, CHO-ZN, Lonza, Horizon, CHO-DG44 etc.).
During the scale-up of perfusion culture from shake tubes to bioreactors, it is commonly observed that peak viable cell density (VCD), product titer, and specific productivity (Qp) decrease to varying degrees.
Serum-free media refers to a cell culture system composed of known chemical components such as nutrients, growth factors, and trace elements without animal serum (such as fetal bovine serum, FBS).
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